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Recent Posts by Statsols:

15 Ways to Reduce Sample Size In Clinical Trials

How do you reduce sample size in clinical trials? Reducing sample size without losing power can be accomplished in one of three principles. This paper examines these methods and demonstrates 15 ways to reduce sample size in clinical trials.

Topics: Power & Sample Size Clinical Trials Reduce Sample Size

Why do phase III clinical trials fail?

Why do Phase III clinical trials fail and how can we improve them? Dr. Grignolo, PhD, Corporate Vice President of PAREXEL International, the multinational life sciences consulting firm, recently examined this issue in a paper titled: Phase III Trial Failures: Costly, But Preventable.

We have reviewed this journal and brought you the primary findings as they appeared in Applied Clinical Trials Volume 25, Issue 8 and also on appliedclinicaltrialsonline.com.

Topics: Power & Sample Size Phase III Failure

What is the difference between Superiority vs. Equivalence vs. Non-inferiority in clinical trial design

The terms superiority, equivalence and non-inferiority are used frequently in publications on clinical trials. To someone starting out in clinical research these three terms and their precise meaning can be quite difficult to grasp. Indeed even experienced researchers have trouble getting their head around these hypotheses. So, what do these terms mean?

Topics: Introduction to Sample Size Clinical Trials nQuery

Data Integration and Visualization

Today’s complex clinical trials yield data sets that are almost unimaginably large and complex. As a result, the process of transforming trial data into usable knowledge simply cannot be accomplished using traditional presentation methods such as conventional charts and graphs.

Topics: Industry News

New lung cancer detection instrument moving to clinical trials stage

Owlstone Nanotech, the developers of a promising new lung cancer detection instrument have announced they are now moving their device into clinical trials. The trials are said to begin later this year in a rapid access lung cancer clinic at Glenfield Hospital in Leicester, England.

Topics: News & Events Industry News

Institute of Medicine releases report “Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk”

Great BLOG Post from By ED SILVERMAN on the Wall Street Journal

Topics: Uncategorized

nQuery Advisor + nTerim used to calculate sample size at St James Hospital, Dublin.

nQuery Advisor + nTerim was used to calculate sample size in a study conducted at St James Hospital, Dublin. The study evaluated the dose intensity and toxicities experienced by patients of normal and increased body mass index BMI treated with FOLFOX chemo- therapy, and demonstrated that overweight patients may tolerate doses based on actual body weight.

Topics: News & Events Power & Sample Size

Clinical trials to begin soon for eZMapp, created by Mapp Biopharmaceutical.

The experimental ZMapp treatment created by Mapp Biopharmaceutical will soon begin human clinical trials in the United States and Liberia, following efforts to boost production capacity.

Topics: Industry News

Clinical trial combo started by Amgen and Merck

Combo clinical trial from Amgen and Merck

Amgen and Merck have launched an early-stage clinical trial pairing their respective cancer immunotherapies, looking to confirm the clinical and commercial promise of combination approaches to cancer.

Topics: Uncategorized

Brincidofovir a very-broad-spectrum antiviral drug?

Brincidofovir, or CMX001, is a broad-spectrum antiviral drug in development by Chimerix. The drug is presently in Phase 3 trials for life-threatening adenovirus in children and adults who have compromised immune systems and for adults with cytomegalovirus infections acquired after hematopoietic stem cells transplants for cancer.

Topics: News & Events