Sample Size Expert Blog

Sample Size and Power for Non-Parametric Analysis

Everything to Know About Sample Size Determination

Projecting How Long Your Trial Will Take | A Practical Guide to Milestone Prediction

2024 Trends in Clinical Trial Design | Complex Trial Design and Impact of Emerging Technologies in Clinical Trials

Designing Robust Group Sequential Trials | Free nQuery Training

Clinical Trial Design | 2023's most popular topics

Trial Design Issues for Phase II Trials

A Practical Guide to Randomization in Clinical Trials

Group Sequential Design Theory and Practice

Practical Guide to Sequential Design

Powering Survival Analysis Clinical Trials

Guest Webinar with InCSD: The Scientific Method and ICH E9 (R1)

Sample Size for Measures of Association

Dealing with Uncertainty in Sample Size Determination

Sample Size for Categorical Endpoints

Sample Size for Regression Models

Clinical Trial Design Trends for 2023

Clinical Trial Design | This year's most popular topics

Guide to Sample Size Re-Estimation in Clinical Trials

Improving Sample Size Using Bayesian Thinking

Sample Size for Non-Inferiority Studies

Randomization in Clinical Trials

Sample Size for Complex Endpoints

Why is Sample Size important?

Sample Size for Statistical Intervals

Advanced Sample Size Determination for Counts and Rates

nQuery is now part of Dotmatics

Sample Size & Prediction Calculation Interactions [Video]

Improving Your Pre-Trial Milestone Predictions

How to predict trial milestones for survival or time to event endpoints

Designing Sequential Clinical Trials

What statistical test should I use?

Crossover & Cluster Randomized Trials

Clinical Trial Design Trends in 2022

Clinical Trial Design | This year's most popular topics

Overcoming Challenges in Survival Analysis [Video]

A New Tool for Clinical Trial Milestone Predictions

How to predict key events in survival analysis trials

Predicting Key Study Milestones

Sample Size for Oncology Trials [Webinar on Demand]

Bayesian Approaches to Interval Estimation & Hypothesis testing

Design and Sample Size for Vaccine Trials | Case Study of Covid-19

Phase II Oncology Trial Designs - Their unique issues & the adaptive solutions

Choosing the right sample size method

2021 Trends In Biostatistics - Latest developments in clinical trial design

This year's most popular clinical trial design topics

Impact of COVID-19 in clinical trials [webinar]

Flexible Clinical Trial Design | Survival, Stepped-Wedge & MAMS

Designing MAMS Trials | Advantages, issues and sample size

Optimizing Oncology Trial Design  (FAQs & Common Issues)

MCP-Mod | Optimizing Phase II Dose Selection

Trends In Biostatistics | What you should know about study design

Alternatives to the p-value & power - The effect on sample size

Why to include Bayesian statistics when planning your frequentist trial

How To Reduce Sample Size | Ethically and responsibly

Sample Size For Survival Analysis

Adaptive Designs for Phase II Trials

Non-inferiority And Equivalence Study Design

Case studies of dealing with study design issues

5 Ways to Optimize Trial Designs

MCP-Mod (Multiple Comparisons Procedure - Modelling) Explained

JSM 2020 - Virtual Event - Everything you need to know

Optimizing Oncology Trial Design [Webinar on Demand]

Recurrent Event Studies - Model choices, pitfalls and group sequential design

Adaptive Design & Early Phase Trials - with Ronan Fitzpatrick & Stephen Senn

FDA Guidance on Conduct of Clinical Trials during the COVID-19 Pandemic

Designing studies with recurrent events

Companies with the most drug approvals for 2019

2020 Trends In Biostatistics [Webinar]

5 Reasons to upgrade to nQuery v8.5 [Video]

An Introduction to Adaptive Clinical Trial Designs | Guest Blog Post

New FDA Guidance on Adaptive Clinical Trial Design

Optimizing Trial Design [Webinar]

Simon's Two Stage Design

Sample Size for Phase II | Simon’s Two-Stage Design and MCP-Mod

What clinical trial challenges do biostatisticians face?

Confidence Interval & Precision Sample Size

Alternatives to the p-value & power? (Webinar)

Unblinded Sample Size Re-Estimation for Survival Analysis

What Are The Top Statistics Blogs?

JSM 2019, Denver - Review from nQuery Sample Size Software

Free Sample Size Software vs nQuery

Why to include Bayesian statistics when planning your frequentist trial (Webinar)

How to Reduce Sample Size ethically and responsibly (Webinar)

Win a $500 Amazon Gift Card at JSM 2019 with nQuery

Dealing with Design Constraints via Hierarchical and Mixed Models

What Statistical Considerations to take in Clinical Trial Designs

Sample Size For Survival Analysis - A guide to planning successful clinical trials (Webinar)

nQuery Summer 2019 Release | 41 new sample size tables

Innovative Strategies For Successful Trial Design (Webinar)

Adaptive Design - Your Strategy for Successful Oncology Trials

2019 Trends In Biostatistics - What you should know about study design (Webinar)

Dealing with Uncertainty in Clinical Trials - with Ronan Fitzpatrick & Prof. Stephen Senn

Bayesian Sample Size & n-of-1 Trials - with Ronan Fitzpatrick & Prof. Stephen Senn

Effect Size & Sensitivity Analysis - with Ronan Fitzpatrick & Prof. Stephen Senn

Sample Size in Clinical Trial Design - with Ronan Fitzpatrick & Stephen Senn

How To Calculate Blinded Sample Size Re-Estimation in Clinical Trials

How To Calculate Unblinded Sample Size Re-Estimation in Clinical Trials

The Advantages & Disadvantages of Unblinded Sample Size Re-Estimation

What is Unblinded Sample Size Re-Estimation in Clinical Trials?

What is Sample Size Re-Estimation?

What is the ROI of nQuery?

The Advantages & Disadvantages of Blinded Sample Size Re-Estimation

What Are Adaptive Clinical Trials? (and why use them)

[Guide] What To Look For In A Sample Size Calculator

5 Reasons Biostatisticians are using nQuery for Adaptive Clinical Trials

Clinical Trial Design & Sample Size Calculation Mistakes To Avoid

15 Ways to Reduce Sample Size In Clinical Trials

New FDA Guidance on Seamless Clinical Trials

Highlights from JSM 2018 | Vancouver

5 Reasons Why Researchers Are Using nQuery To Calculate Bayesian Assurance

Say hello to the nQuery Sample Size Software Team at JSM 2018

The 5 Essential Steps for Sample Size Determination (Webinar)

Practical Methods to Overcome Sample Size Challenges (Webinar)

A Brief Overview of Bayesian Analysis for Biostatisticians

5 Reasons Why Pharma Companies Are Calculating Bayesian Assurance

Maximum-Tolerated Dose & the Continual Reassessment Method

Why Frequentists are using Bayesian Statistics in Clinical Trial Design

Top 10 Corporate Clinical Trial Sponsors of 2016

Wider Integration of Cost Considerations in Sample Size

The Effect of Adaptive Trials and Sample Size Re-estimation

Integrating Uncertainty in Parameter Estimates

Most Popular Clinical Trial Drugs of 2016

Why do phase III clinical trials fail?

What is the difference between Superiority vs. Equivalence vs. Non-inferiority in clinical trial design

Making it personal: N-of-1 trials, allowing for individuality but not overdoing it

Intact social cognitive processes in outpatients with anorexia nervosa: a pilot study

STUDY: Pre-surgical depression and anxiety and recovery following coronary artery bypass graft surgery

Clinical Trials Data Dive - Results from 220,000 clinical trials

Power Combined with Precision Helps Improve Sample Size Justification

Thoughts on the ASA P Values Statement

Monday at JSM 2015, what are you attending?

An Overview of Multiple Imputation in SOLAS for Missing Data 5.0

Missing Data - A Pervasive Problem in Data Analysis

Why is Sample Size Important?

Data Integration and Visualization

New lung cancer detection instrument moving to clinical trials stage

Institute of Medicine releases report “Sharing Clinical Trial Data: Maximizing Benefits, Minimizing Risk”

nQuery Advisor + nTerim used to calculate sample size at St James Hospital, Dublin.

Clinical trials to begin soon for eZMapp, created by Mapp Biopharmaceutical.

Clinical trial combo started by Amgen and Merck

Brincidofovir a very-broad-spectrum antiviral drug?

Johnson and Johnson to Start Ebola Vaccine Trial in 2015

What is a Meta Analysis

GSK to start Clinical Trial on Ebola Vaccine

Happy Birthday Statistical Solutions

nQuery Advisor + nTerim now sold on subscription.

Happy 4th July!

Clinical trial data to be made available for download.

Homeward bound from DIA

Sample Size

Infographic: The process of discovering and bringing a new drug to the public

FDA recommends bioequivalence standards for 26 drugs

The DIA 2014 50th Annual Meeting

New Release - nQuery Advisor + nTerim 3.0

Introducing the nQuery Advisor + nTerim Campus Licence.

nQuery Advisor User Group for Clinical Trials.

A Celebration of Don Rubin on His 70th Birthday

The World of Statistics launch new website

New Year, New Website

The Prevention and Treatment of Missing Data in Clinical Trials

Free Webinar…..Multiple Imputation in Pharmaceutical Clinical Trials

ISI Dublin + JSM Miami Reports

Report on 4th Workshop on Analysis of Incomplete Data (AID), Bamberg, Germany

PSI Expert Group on Missing Data

Power and Sample Size for Group Sequential Trials

BMDP Statistical Software in Cutting Edge Research