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Stephen Senn, Luxembourg Institute of Health

Stephen Senn, Luxembourg Institute of Health

A leading global authority on clinical biostatistics, Stephen Senn is a former member of the Statsols statistical advisory board and he currently serves as a consultant to our statistical development team. Stephen is currently Head of Competence Centre for Methodology and Statistics with the Luxembourg Institute of Health.

Recent Posts by Stephen Senn, Luxembourg Institute of Health:

Making it personal: N-of-1 trials, allowing for individuality but not overdoing it

N-of-1 trials are the application of the machinery of randomised clinical trials to the individual patient. Episodes of treatment rather than individual patients become the fundamental unit of inference and patients are repeatedly randomised to an experimental and a control treatment (say) in order to establish the effect of treatment. Popular designs involve cycles of episodes of treatment with the patient being assigned to a random order within cycles. (Continued below)

Topics: Power & Sample Size Clinical Trials N-of-1 Trials Stephen Senn