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nQuery Sample Size Calculator has been featured in another interesting study, this time published in the Journal of Behavioral Medicine.
The study states that "co-morbid depression is commonly observed in patients suffering from coronary heart disease (Dickens 2015). Two landmark studies documented the impact of depression on survival following coronary artery bypass graft (CABG) surgery".
The study "aimed to explore the combined contribution of pre-surgical depression and anxiety symptoms for recovery following coronary artery bypass graft (CABG) using data from 251 participants. Participants were assessed prior to surgery for depression and anxiety symptoms and followed up at 12 months to assess pain and physical symptoms, while hospital emergency admissions and death/major adverse cardiac events (MACE) were monitored on average 2.68 years after CABG."
"After controlling for covariates, baseline anxiety symptoms, but not depression, were associated with greater pain (β = 0.231, p = 0.014) and greater physical symptoms (β = 0.194, p = 0.034) 12 months after surgery.
On the other hand, after controlling for covariates, baseline depression symptoms, but not anxiety, were associated with greater odds of having an emergency admission (OR 1.088, CI 1.010–1.171, p = 0.027) and greater hazard of death/MACE (HR 1.137, CI 1.042–1.240, p = 0.004). These findings point to different pathways linking mood symptoms with recovery after CABG surgery."
(Below is an extract from the results of the study. For full details of how nQuery Sample Size Calculator was used including details regards power analysis, outcome variables, covariates and statistical methods, please read the Full Study here.)
Cite: Poole, L., Ronaldson, A., Kidd, T. et al. J Behav Med (2016). doi:10.1007/s10865-016-9775-1
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