Sample Size Expert Blog

Highlights from JSM 2018 | Vancouver

The nQuery Sample Size Software team recently made the trip from our Irish HQ to Vancouver in Canada for JSM 2018. Read a quick overview of the highlights & insights from JSM including the Bayesian technology workshop that our Head of Statistics - Ronan Fitzpatrick - hosted at JSM 2018.

Topics: JSM

5 Reasons Why Researchers Are Using nQuery To Calculate Bayesian Assurance

The pharmaceutical industry is increasingly turning to Bayesian methods in an attempt to improve efficiency and enhance decision making at many stages. See the top 5 reasons why researchers are using nQuery sample size software to calculate Assurance (Bayesian Power).

Topics: Clinical Trials Bayesian Assurance nQuery Bayes sample size determination

Say hello to the nQuery Sample Size Software Team at JSM 2018

If you are going to JSM this year, drop by the nQuery Sample Size Software booth (#328) to meet some members of our team, talk all things sample size and give us your thoughts on nQuery! We would love to see you there.

Topics: JSM

The 5 Essential Steps for Sample Size Determination (Webinar)

Re-watch our popular webinar where we list the The 5 Essential Steps for Sample Size Determination. At each step, Eimear will highlight the important function it plays and how to avoid the errors that will negatively impact your sample size determination and therefore your study.

Topics: Power & Sample Size sample size determination webinar sample size challenges Effect Size how to calculate sample size

Practical Methods to Overcome Sample Size Challenges (Webinar)

Re-watch our popular webinar where we examine some of the most common and practical challenges you will experience while calculating sample size for your study. These challenges are split into two categories: 1. Overcoming Sample Size Calculation Challenges (Survival Analysis Example) & 2. Overcoming Study Design Challenges (Vaccine Efficacy Example).

Topics: Bayesian Assurance sample size determination webinar Case-Control Analysis Alternative Randomization Methods sample size challenges Effect Size Drop Out Rare Events

A Brief Overview of Bayesian Analysis for Biostatisticians

Bayesian methods are becoming more common in clinical trials. Previously, a lack of computing in sample size software hindered the use of these methods, but improvements in the area have led to more widespread use. To examine what’s new and different about Bayesian sample size determination, we first need to consider what’s done in a traditional setting.

Topics: Introduction to Sample Size Reduce Sample Size Bayesian Assurance nQuery Bayes Dose Escalation Continual Reassessment Method (CRM)

5 Reasons Why Pharma Companies Are Calculating Bayesian Assurance

The pharmaceutical industry is increasingly turning to Bayesian methods in an attempt to improve efficiency and enhance decision making. Assurance (Bayesian Power) is becoming a key feature of these Bayesian methods. This is not to replace traditional power but to complement it.

Topics: Clinical Trials Bayesian Assurance nQuery Bayes sample size determination

Dose Escalation: Quickly determine the Maximum-Tolerated Dose through Continual Reassessment Method

A key drawback of the traditional 3+3 design in dose escalation is its slow processing of data to reach the target dose. In contrast, the Continual Reassessment Method designs produce an expedited convergence to the target dose or the doses near target.

Topics: Clinical Trials Dose Escalation Continual Reassessment Method (CRM)

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